This toolkit is designed to empower you with tools that complement the Framework for Novel Digital Clinical Measures, enabling you to:

• Investigate how a novel method for assessing agreement between measures performs in a simulated analytical validation study, even when the measures lack directly comparable units.
• Compare the novel method with established approaches to assessing agreement in similar studies.
• Explore how common study design factors influence the estimates gathered from these methods.
• Experiment with a realistic data generation mechanism to simulate scenarios for your own novel digital clinical measures.

The methodology behind this toolkit is described in this manuscript.

Access the simulation toolkit on GitHub

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